Intern
Institut für Hygiene und Mikrobiologie

Curriculum vitae Prof. Dr. med. Alexandra Schubert-Unkmeir

Academic career:    
1989-1996   Studies of Medicine at the Medical School Hannover
1997-1998   AiP at the Institute for Medical Microbiology, University of Mainz
1999-2002   Research Fellow at the Institute for Hygiene and Microbiology Würzburg
since 2002   Group leader at the Institute for Hygiene and Microbiology Würzburg
2006   Specialist for Microbiology, Virology and Infection Epidemiology (Bayerische Landesärztekammer)
2009   Habilitation: „Medical Microbiology“, University of Wuerzburg, mentor: Prof. Dr. M. Frosch
06/2010-03/2012   ‚Akademische Oberrätin auf Zeit’ at the Institute of Hygiene and Microbiology, Wuerzburg
2011   Appointment associate professor (W2) for Medical Microbiology and Immunology at the Institute for Clinical Microbiology and Immunology, University of Erlangen (Prof. Dr. C. Bogdan) (declined)
04/2012   Associate professor (Cellular Microbiology; W2), at the Institute of Hygiene and Microbiology, Wuerzburg
Major research interests:
Infection biology, Neisseria meningitidis, bacteria-host cell interaction, interaction of N. meningitidis with cells of the blood-cerebrospinal-fluid barrier, signal transduction, cytoskeletal dynamics and signalling, transcriptional regulators
Fellowships/Awards:
2009   Becton-Dickinson Scientific Award (German Society for Hygiene and Microbiology)
Research Topics
Molecular basis of host-pathogen interaction in meningococcal meningitis
Project Management
2002-2005   Interaction of Neisseria meningitidis with cells of the human blood brain barrier Schwerpunktprogramm SPP1130 “Infektionen des Endothels”
2005-2006   Pathologische Aktivierung humaner Thrombozyten durch Meningokokken und Gruppe B Streptokokken: Molekulare Mechanismen und klinische Bedeutung (IZKF Würzburg, Projekt A33)
2007-2009   Untersuchungen zur Integrin-vermittelten Signalweiterleitung in Endothelzellen nach Infektion mit N. meningitidis“ (DFG-Normalverfahren, SCHU2394/1-1)
2010-2013   Untersuchungen zur Integrin-vermittelten Signalweiterleitung in Endothelzellen nach Infektion mit N. meningitidis“ (DFG-Normalverfahren, SCHU2394/1-2)
2014-2015   Role of non-receptor tyrosine kinases and activated signaling pathways in bacterial adherence and invasion of host cells (BaCaTec (Bavaria California Technology Center), Förderprojekt Nr. 12 [2013-2])
2014-2016   Untersuchung zur funktionellen Relevanz von Sphingomyelinasen und Ceramiden in der Pathogenese der Meningokokkeninfektion“ (SCHU 2394/2-1; Teilprojekt P03 im Rahmen der Forschergruppe FOR 2123 „Sphingolipids in infection control“)
2016-2019   Meningococcal ligands and molecular targets required for adhesion and penetration of the blood-cerebrospinal fluid barrier under shear stress (Teilprojekt im Rahmen des GRK2157 3D Tissue Models for Studying Microbial Infections by Human Pathogens)
2018-2019   Blood brain barrier failure during bacterial and viral infections (BaCaTec (Bavaria California Technology Center), Förderprojekt)
2017-2019   Untersuchung zur funktionellen Relevanz von Sphingomyelinasen und Ceramiden in der Pathogenese der Meningokokkeninfektion“ (SCHU 2394/2-2; Teilprojekt P03 im Rahmen der Forschergruppe FOR 2123 „Sphingolipids in infection control“)
Editorial work:
Reviews for: Journal of Molecular Microbiology International Journal of Medical Microbiology, Infection and Immunity, Cellular Microbiology, Nature Reviews, Plos Pathogens
Scientific Reviewer for The Meningitis Research Foundation