IHM leads investigation on carriage in the elderly of various pathogens colonizing the nasopharynx...
... The IBI consortium previously funded by the RKI comprised the reference laboratories for meningococci and H. influenzae, streptococci, and diphtheria. The three laboratories jointly conducted the carriage study, which has been published in PLoS One by Drayß et al (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212052). In the article, the autors thank "all participants, in particular all care and sheltered housing facilities, the rehabilitation hospital, as well as the senior citizen’s office and the public health office of Wuerzburg."
Drayß M, Claus H, Hubert K, Thiel K, Berger A, Sing A, Linden MV, Vogel U, Lâm TT. Asymptomatic carriage of Neisseria meningitidis, Haemophilus influenzae, Streptococcus pneumoniae, Group A Streptococcus and Staphylococcus aureus among adults aged 65 years and older.
Objective The aim of this study was to determine the prevalence of Neisseria meningitidis, Haemophilus influenzae, Streptococcus pneumoniae, group A Streptococcus (GAS), and Staphylococcus aureus in asymptomatic elderly people and to unravel risk factors leading to colonization. Methods A multi-centre cross-sectional study was conducted including 677 asymptomatic adults aged 65 years or more, living at home or in nursing homes. Study areas were Greater Aachen (North-Rhine-Westphalia) and Wuerzburg (Bavaria), both regions with medium to high population density. Nasal and oropharyngeal swabs as well as questionnaires were collected from October 2012 to May 2013. Statistical analysis included multiple logistic regression models. Results The carriage rate was 1.9% ([95%CI: 1.0–3.3%]; 13/677) for H. influenzae, 0.3% ([95%CI: 0–1.1%]; 2/677) for N. meningitidis and 0% ([95% CI: 0–0.5%]; 0/677) for S. pneumoniae and GAS. Staphylococcus aureus was harboured by 28.5% of the individuals ([