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Intern
    Institut für Hygiene und Mikrobiologie

    Doctoral Researcher (PhD, f/m/d)

    18.06.2020

    New diagnostic and therapeutic strategies for treatment of fungal keratitis using a 3D cornea model

    The Institute for Hygiene and Microbiology of the University of Würzburg combines clinical diagnostics and state of the art research in infectious diseases with services in patient care. The Chair for Medical Microbiology and Mycology is among the internationally leading centers for the diagnosis of invasive fungal infections. Our research focusses on the epidemiology, diagnosis and infection biology of invasive fungal pathogens. To strengthen our team, we invite talented and motivated candidates to apply for positions as:

     

    Doctoral Researchers (PhD, f/m/d)

    (TVL-E13, 65%)

     

    The successful candidate will work on new diagnostic and therapeutic strategies for treatment of fungal keratitis using a 3D cornea model. Fungal keratitis is a devastating infection, which frequently results in corneal transplantation or loss of the eye. Within the PhD project, we aim to establish new models to study this disease and evaluate potential new treatment strategies. The project will be carried out in close collaboration with the Department of Ophthalmology of the University Hospital Würzburg and the Fraunhofer Institute for Silicate Research ISC in Würzburg and is integrated into the Interdisciplinary Center for Clinical Research (IZKF).


    Your research tasks may include

    • Optimisation of an existing human 3D model (tissue engineering)
    • Susceptibility testing of clinically relevant fungi
    • In vitro simulation of fungal infections
    • Confocal microscopy and life cell imaging
    • Efficacy tests for fungicidal or protective effects of new substances
    • RNA isolation and transcriptome analysis

     

    Your profile

    • Interest in infection biology, cell biology, immunology and/or molecular biology
    • MSc (or equivalent) in natural sciences (Biology, Biochemistry or related fields) - candidates in the final stages of obtaining their degree are eligible to apply
    • Background in microbiology, biochemistry, cell biology, immunology or related fields
    • Experience in cell culture methodologies, molecular biology/genetics, fluorescence/confocal microscopy, and immunology is advantageous

    The position is available immediately and initially limited to 3 years. Salary is paid according to German TV-L (salary agreement for public service employees).

    The University of Würzburg is an equal opportunities employer and places emphasis on fostering career opportunities for women. Qualified women are therefore strongly encouraged to apply. The University of Würzburg intends to raise the number of disabled persons in its employment. In the case of equally qualified applicants, disabled persons will preferentially be considered.

    For further information please contact Prof. Dr. Oliver Kurzai (okurzai@hygiene.uni-wuerzburg.de).

    Complete applications in English or German should include a letter of interest, curriculum vitae, a brief statement of research experiences, a list of two potential references, and a full academic record (copies of degree certificates) and be submitted as a single pdf file by email (subject line PhD_7/2020_IHM) by July 15th 2020 to

    sekretariat-kurzai@hygiene.uni-wuerzburg.de

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