Intern
    Institut für Hygiene und Mikrobiologie

    Publications

    2017

    Harrison O. B., C. Schoen, A. C. Retchless, X. Wang, K. A. Jolley, J. E. Bray, and M. C. J. Maiden (2017) Neisseria genomics: current status and future perspectives.. Pathog Dis in press

    Heidrich N., S. Bauriedl, L. Barquist, L. Li, Schoen C*, and Vogel J* (2017) The primary transcriptome of Neisseria meningitidis and its interaction with the RNA chaperone Hfq. Nucleic Acids Res in press

    Ampattu B. J., L. Hagmann , C. Liang, M. Dittrich, A. Schlüter, J. Blom, E. Krol, A. Goesmann, A. Becker, T. Dandekar, T. Müller, and C. Schoen (2017) Transcriptomic buffering of cryptic genetic variation contributes to meningococcal virulence. BMC Genomics 18: 282

    Klughammer J., M. Dittrich, J. Blom, V. Mitesser , U. Vogel, M. Frosch, A. Goesmann, T. Müller, and C. Schoen (2017) Comparative genome sequencing reveals within-host genetic changes in Neisseria meningitidis during invasive disease. PLoS One. 12:e0169892

    Segerer F. J., K. Seeger, A. Maier, C. Hagemann, C. Schoen, M. van der Linden, A. Streng, M. A. Rose and J. G. Liese (2017) Therapy of 645 children with parapneumonic effusion and empyema-A German nationwide surveillance study. Pediatr Pulmonol 52:540-7

    Schoenfelder S. M., Y. Dong, A. T. Feßler, S. Schwarz, C. Schoen, R. Köck and W. Ziebuhr (2017) Antibiotic resistance profiles of coagulase-negative staphylococci in livestock environments. Vet Microbiol. 200:79-87

    2016

    Tappe D., M. Sulyok, T. Riu, L. Rózsa, I. Bodó, C. Schoen, B. Muntau, G. Babocsay and R. Hardi (2016) Co-infections in Visceral Pentastomiasis, Democratic Republic of the Congo. Emerg Infect Dis 22:1333-9

    Koch T., C. Schoen, B. Muntau, M. Addo, H. Ostertag, B. Wiechens, and D. Tappe (2016)  Molecular Diagnosis of Human Taenia martis Eye Infection. Am J Trop Med Hyg 94:1055-7

    2015

    Stijnis, K., A. C. Dijkmans, A. Bart, L. A. Brosens, B. Muntau, C. Schoen, T. F. Barth, T. van Gulik, T. van Gool, M. P. Grobusch and D. Tappe (2015) Echinococcus vogeli in immigrant from Suriname to the Netherlands. Emerg Infect Dis 21:528-3

    2014

    Schoen, C., L. Kischkies, J. Elias and B. J. Ampattu (2014) Metabolism and virulence in Neisseria meningitidis. Front Cell Infect Microbiol 4:114

    2013

    Zhang, Y., N. Heidrich, B. J. Ampattu, C. Gunderson, H. S. Seifert, C. Schoen, J. Vogel and E. J. Sontheimer (2013) Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis. Mol Cell 50: 488-503

    Mordhorst, I.L., A. Menzer, M. Abele-Horn und C. Schoen (2013) Potential und gegenwärtiger Einsatz der MALDI TOF-Massenspektrometrie in der mikrobiologischen Diagnostik. Mikrobiologe 23:30-35

    Tappe, D., K. Ernestus, S. Rauthe, C. Schoen, M. Frosch, A. Müller and A. Stich (2013) Initial patient cluster and first positive biopsy findings in an outbreak of acute muscular Sarcocystis-like infection in travelers returning from Tioman island, Peninsular Malaysia, in 2011. J Clin Microbiol 51:725-726


    2012


    Pawlik, M.-C., K. Hubert, B. Joseph, H. Claus, C. Schoen and U. Vogel
    (2012) The zinc-responsive regulon of Neisseria meningitidis comprises seventeen genes under control of a Zur element. J Bacteriol 194: 6594-603

    Schork, S., A. Schlüter, J. Blom, S. Schneiker-Bekel, A. Pühler, A. Goesmann, M. Frosch and C. Schoen (2012) Genome Sequence of a Neisseria meningitidis Capsule Null Locus Strain from the Clonal Complex of Sequence Type 198. J Bacteriol 194: 5144-5.

    Tappe, D., M. H. Schulze, A. Oesterlein, M. Abele-Horn, S. Baron, D. Durchholz, H. J. Langen, B. Jany and C. Schoen (2012) Molecular detection of Campylobacter jejuni as a cause of culture-negative spondylodiscitis. J Clin Microbiol 50: 1499-500

    Joseph, B., M. Frosch, C. Schoen and A. Schubert-Unkmeir (2012) Transcriptome analyses in the interaction of Neisseria meningitidis with mammalian host cells. Methods Mol Biol 799: 267-93.


    2011

    Heisig, M., A. Frentzen, B. Bergmann, K. Galmbacher, I. Gentschev, C. Hotz, C.  Schoen,  J. Stritzker, J. Fensterle, U. R. Rapp and W. Goebel
    (2011) Specific antibody-receptor interactions trigger InlAB-independent uptake of Listeria monocytogenes into tumor cell lines. BMC Microbiology 11:163
    Joseph, B. R. F. Schwarz, B. Linke, J. Blom, A. Becker, H. Claus, A. Goesmann, M. Frosch, T. Müller, U. Vogel and C. Schoen
    (2011) Virulence evolution of the human pathogen Neisseria meningitidis by recombination in the core and accessory genome. PLoS ONE 6:e18441

    Schoen, C., J. Weber-Lehmann, J. Blom, B. Joseph, A. Goesmann, A. Strittmatter and M. Frosch (2011) Whole-genome sequence of the transformable Neisseria meningitidis serogroup A strain WUE2594. J Bacteriol 193:2064-5.

    Schielke, S., C. Spatz, R. F. Schwarz, B. Joseph, C. Schoen, S. M. Schulz, K. Hubert, M. Frosch, A. Schubert-Unkmeir and O. Kurzai (2011) Characterization of FarR as a highly specialized, growth phase-dependent transcriptional regulator in Neisseria meningitidis. Int J Med Microbiol 301:325-33.

    Tappe, D., M. Meyer, A. Oesterlein, A. Jaye, M. Frosch, C. Schoen and N. Pantchev (2011) Transmission of Armillifer armillatus Ova at Snake Farm, The Gambia, West Africa. Emerg Infect Dis 17:251-4


    2010

    Valenza, G., Radike, C. Schoen, S. Horn, A. Oesterlein, M. Frosch, M. Abele-Horn and H. Hebestreit (2010) Resistance to tobramycin and colistin in isolates of Pseudomonas aeruginosa from chronically colonized patients with cystic fibrosis under antimicrobial treatment. Scan J Infect Dis 42:885-9

    Joseph, B., S. Schneiker-Bekel, A. Schramm-Glück, J. Blom, H. Claus, B. Linke, R. Schwarz, A. Becker, A. Goesmann, M. Frosch and C. Schoen (2010) Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence. J Bacteriol 192:5363-77

    Schwarz, R., B. Joseph, G. Gerlach, A. Schramm-Glück, K. Engelhardt, M. Frosch, T. Müller and C. Schoen (2010) Evaluation of one- and two-color gene expression arrays for microbial comparative genome hybridization analyses in routine applications. J Clin Microbiol 48:3105-10

    Valenza, G., B. Joseph, J. Elias, H. Claus, A. Oesterlein, K. Engelhard, J. Elias, D. Turnwald, M. Frosch, M. Abele-Horn and C. Schoen (2010) First survey of metallo-β-lactamases in clinical isolates of Pseudomonas aeruginosa in an German university hospital. Antimicrob Agents Chemother 54:3493-7.

    Elias, J., C. Schoen, G. Heinze, G. Valenza, E. Gerharz, H. Riedmüller and U. Vogel (2010) Nosocomial outbreak of VIM-2 metallo-beta-lactamase producing Pseudomonas aeruginosa associated with retrograde urography. Clin Microbiol Infec 16:1494-1500
    Vogel, U., C. Schoen and J. Elias
    (2010) Population Genetics of Neisseria meningitidis. In: Robinson, D. A., D. Falush and E. J. Feil, eds. Bacterial Population Genetics in Infectious Disease. Oxford, UK: Wiley-Blackwell; pp. 247-67


    2009

    Schoen C., C. Unzicker, G. Stuhler, J. Elias, H. Einsele, G. U. Grigoleit, M. Abele-Horn and S. Mielke (2009) Life threatening infection of a neutropenic patient with a daptomycin highly resistant strain of Corynebacterium jeikeium. J Clin Microbiol 47:457-9.

    Gerlach, G., M. Anthony, M. Deadman, D. Hood, C. Schoen and J. Reidl (2009) Oxidative stress response and virulence in Haemophilus influenzae. Int J Med Microbiol 300:218-28

    Mordhorst, I. L., H. Claus, C. Ewers, M. Lappann, C. Schoen, J. Elias, J. Batzilla, U. Dobrindt, L. H. Wieler, A. K. Bergfeld, M. Mühlenhoff and U. Vogel (2009) O-acetyltransferase gene neuO is segregated according to phylogenetic background and contributes to environmental desiccation resistance in Escherichia coli K1. Env Microbiol 11:3154-65

    Schwarz, R., P. N. Seibel, S. Rahmann, C. Schoen, M. Huenerberg, C. Müller-Reible, T. Dandekar, R. Karchin, J. Schultz and T. Müller (2009) Detecting species-site dependencies in large multiple sequence alignments. Nucl Acids Res 37: 8959-8968

    Schoen, C., H. Tettelin, J. Parkhill and M. Frosch (2009) Genome flexibility in Neisseria meningitidis. Vaccine 27S: B103-B111

    Schubert-Unkmeir, A., A. Schramm-Glück, M. Frosch and C. Schoen (2009) Transcriptome analyses in the interaction of Neisseria meningitidis with mammalian host cells. Methods Mol Biol 470: 5-27.

    Schoen C. and S. Hammerschmidt (2009) Genomforschung an bakteriellen Meningitiserregern. In: Akute bakterielle Meningitis. 2nd edition, Bremen: UNI-MED Verlag; pp. 88-97.

    Schoen, C. and O. Kurzai (2009) Wehe wenn sie losgelassen… Warum machen Meningokokken krank? BIOFORUM 5


    2008

    Schoen, C., D. I. Loeffler, A. Frentzen, S. Pilgrim, W. Goebel and J. Stritzker (2008) Listeria monocytogenes as novel carrier system for the development of live vaccines. Int J Med Microbiol 298: 45-58.

    Schoen, C., J. Blom, H. Claus, A. Schramm-Glück, P. Brandt, T. Müller, A. Goesmann A, B. Joseph, S. Konietzny, O. Kurzai, C. Schmit, T. Friedrich, B. Linke, U. Vogel U and M. Frosch (2008) Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis. Proc Natl Acad Sci U S A 105: 3473-3478.

    Schoen, C., J. Stritzker, T. M. Fuchs, S. Weibel, I. Gentschev, A. A. Szalay and W. Goebel (2008) Use of intracellular bacteria for the development of tools for tumor therapy and the detection of novel antibacterial targets. In: Sleator R. and C. Hill, eds. Patho-Biotechnology. Austin, TX: Landes Biosciences; pp. 112-21

    Schoen, C., C. Müller, J. Blom, B. Linke, T. Müller, A. Goesmann, H. Claus, R. Berner, U. Vogel and M. Frosch (2008) Einem heimtückischen Killer auf der Spur. GENOMXPRESS 3, 14-16.


    2007

    Schoen, C., B. Joseph, H. Claus, U. Vogel U and M. Frosch (2007) Living in a changing environment: insights into host adaptation in Neisseria meningitidis from comparative genomics. Int J Med Microbiol 297: 601-613.

    Claus, H., U. Vogel, H. Swiderek and C. Schoen (2007) Microarray analyses of meningococcal genome composition and gene regulation. FEMS Microbiol Rev 31: 43-51.


    2006

    Valenza G., S. Burgemeister, H. Girschick, C. Schoen,  S. Veihelmann, A. Moter, V. Haban, U. Vogel and U. Schlagenhauf (2006) Analysis of the periodontal microbiota in childhood-type hypophosphatasia. Int J Med Microbiol 296:493-500.

    Loeffler D.I., C. Schoen, W. Goebel W and S. Pilgrim (2006) Comparison of different live vaccine strategies in vivo for delivery of protein antigen or antigen-encoding DNA and mRNA by virulence-attenuated Listeria monocytogenes. Infect Immun 74:3946-57.

    Schoen C. and H. Claus (2006) Neisseria meningitidis genome sequencing projects. In: Frosch M, Maiden MC, eds. Handbook of Meningococcal Disease: Pathogenicity and Prevention. Weinheim: Wiley-VCH; pp. 77-97.

    Schoen C., H. Claus, U. Vogel and M. Frosch (2006) Genomes of pathogenic Neisseria species. In: Hacker J, Dobrindt U, eds. Pathogenomics. Weinheim: Wiley-VCH; pp. 231-55.


    2005

    Schoen C., A. Kolb-Mäurer, G. Geginat, D. Loeffler, B. Bergmann, J. Stritzker, A. Szalay, S. Pilgrim and W. Goebel (2005) Bacterial delivery of functional messenger RNA to mammalian cells. Cell Microbiol 7: 709-724.

    Stritzker J., C. Schoen and W. Goebel (2005) Enhanced synthesis of internalin A in aro mutants of Listeria monocytogenes indicates posttranscriptional control of the inlAB mRNA. J Bacteriol 187: 2836-45.

    Pilgrim S., C. Schoen, J. Stritzker, A. Frenzen, D. Loeffler, I. Gentschev and W. Goebel (2005) Virulence-attenuated intracellular bacterial pathogens for the development of novel live vaccines. Nova Acta Leopoldina NF 92: 235-240.


    2004

    Strizker J., J. Janda, C. Schoen, M Taupp, S. Pilgrim, I. Gentschev, P. Schreier, G. Geginat  and W. Goebel (2004) Growth, virulence, and immunogenicity of Listeria monocytogenes aro mutants. Infect Immun 72: 5622-9.

    Schoen C., J. Stritzker, W. Goebel und S. Pilgrim (2004) Bacteria as DNA vaccine carriers for genetic immunization Int J Med Microbiol 294: 319-335.


    2003

    Pilgrim S., J. Stritzker, C. Schoen, A. Kolb-Mäurer, G. Geginat, M. J. Loessner, I. Gentschev and W. Goebel (2003) Bactofection of mammalian cells by Listeria monocytogenes: improvement and mechanism of DNA delivery. Gene Ther 10: 2036-45.


    2002

    Schoen C., U. Reichard, M. Monod, H. D. Kratzin and R. Rüchel (2002) Molecular cloning of an extracellular aspartic proteinase from Rhizopus microsporus and evidence for its expression during infection. Med Mycol 40: 61-71.

    Frantz S., A. Greiner, C. Schoen, P. Langmann und H. Klinker (2002) A sebaceous tumor in a patient with acquired immunodeficiency syndrome. Eur J Med Res 7: 135-7.

    Schoen C. (2002) Von Menschen und Läusen: Leopoldina International Symposium „Parasitism, Commensalism, Symbiosis - Common Themes, Different Outcome“. BIOSpektrum 6: 733.


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    Josef-Schneider-Straße 2
    97080 Würzburg

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